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WASHINGTON asics gel lyte 3 soldes , April 30 (Xinhua) -- U.S. researchers said Wednesday that it is possible to rebuild large amounts of muscles severely damaged in traumatic accidents or military wounds by implanted tissues of pig bladders.
Researchers from the University of Pittsburgh tested the experimental technique on five male patients, who had lost between 58 and 90 percent of limb muscle, and found that three of them had a 25 percent improvement in function.
"This new study is the first to show replacement of new functional muscle tissue in humans, and we're very excited by its potential," Stephen Badylak, senior investigator at the University of Pittsburgh.
"These are patients who can't walk anymore asics gel lyte 5 soldes , can't get out of a car, can't get up and down from a chair, can't take steps without falling. Now we might have a way of helping them get better," Badylak said.
Large amounts of muscle can be lost as a result of trauma, such as a car accident, a sports injury asics gel quantum 360 knit 2 pas cher , or even an explosive device. There is no treatment for such volumetric muscle loss and native muscle is unable to regenerate to that extent, to fully recovery function and tissue volume. Instead, scar tissue can form to fill the gap.
Stem cells have been shown to help damaged tissue regenerate, but in most cases, stem cells should be taken out, isolated and grown into the cell of choice asics gel quantum 360 knit 2 noir , and then injected back into patients.
Badylak's team, however, used the extracellular matrix (ECM) from pig bladders to attract stem cells to the site of injury to promote regrowth of muscle.
According to the researchers, pig bladder ECM has been used for many years as the basis for medical products for hernia repair and treatment of skin ulcers. It is the biologic scaffold that remains left behind after cells have been removed.
After first showing the ECM method worked in mice with severely injured hind limbs, the researchers started a clinical trial involving five men, all at least six months removed from the time of injury asics gel quantum 360 soldes , and for whom surgery and physical therapy had proved unsuccessful.
Three of the patients were in the military; two had thigh injuries from bombs while one had an exercise-induced calf injury. The other two patients were civilians with calf injuries from skiing accidents.
Before surgery, all patients completed a 12- to 16-week physical therapy program that focused specifically on their individual functional deficits. The program continued until their function and strength plateaued for a minimum of two weeks, with no signs of further improvement.
Then, the researchers surgically implanted a "quilt" of compressed ECM sheets designed to fill into their injury sites, and within 48 hours of the operation, the participants resumed physical therapy for up to 26 additional weeks.
The researchers found that three participants onitsuka tiger mexico 66 soldes , including the two who had thigh injuries and one who had a calf injury, were stronger by 25 percent six months after the surgery and that biopsies and scans all indicated that muscle growth had occurred.
One thigh-injured patient improved on the "single hop test" by 1,820 percent, and the other had a 352 percent improvement in a chair lift test and a 417 percent improvement in the single-leg squat test.
Two other participants with calf injuries did not have such dramatic results, but both improved on at least one functional measure and said they felt better.
"This work represents an important step forward in our ability to repair tissues and improve function with materials derived from natural proteins. There will be more options to help our patients, " said study co-author Peter Rubin onitsuka tiger soldes , chair of the department of plastic surgery at the University of Pittsburgh.
"We think it's remarkable that this approach was able to improve function among patients who were all well past the acute injury response phase and were not helped by the standard surgical procedures they had already had," Rubin added.
The findings were published in the U.S. journal Science Translational Medicine.
ACCRA, Oct. 17 (Xinhua) -- The Ghana Medical Association (GMA) has cautioned the government against hosting the 2015 African Cup of Nations (AFCON), a request by the Confederation of African Football (CAF).
This followed reports that Morocco, the original hosts, were considering withdrawing for fear of possible flow of the dreaded Ebola Virus Disease (EVD) that has killed more than 4 www.chaussurerunningsoldes.fr ,500 persons in Guinea, Liberia and Sierra Leone.
Mahama Ayariga, minister of Youth and Sports, confirmed Thursday to Citi Sports that Ghana had been approached by CAF about the possibility of hosting the biannual tournament in 2015.
"CAF wrote to us a few days ago actually and indicated that Morocco had given strong indications that they will pull out if CAF did not change the date," he said.
Local media also indicated that 2013 AFCON hosts, South Africa chaussures asics running homme soldes , were being considered by the governing body of African football as possible replacement hosts.
Speaking to Citi News, the Deputy General Secretary of the GMA, Dr. Justice Yankson, said it would be risky for the government to accept the request from CAF.
"If people are going to be here for more than or close to a month, some could come in at a point where they do not have a full blown infection or are not exhibiting the symptoms.
"But the symptoms could come in after they have already entered the country. That is something we need to think about. Before we take a final decision, we really need to sit down and do our homework well chaussures asics running soldes ," he emphasized.
The World Health Organization (WHO) warned on Tuesday there could be up to 10,000 new Ebola cases per week in Guinea, Liberia and Sierra Leone by the end of this year.
The Moroccan youth and sports minister Mohamed Ouzzine said on Thursday though they had not yet withdrawn as hosts, they considered the advice of the World Health Organization (WHO. Wholesale Jerseys Wholesale Jerseys China Free Shipping Cheap Sports Jerseys Free Shipping Cheap New NBA Jerseys Cheap T-shirts Cheap NCAA Jerseys Wholesale Cheap Soccer Jerseys China Cheap NHL Hoddies Cheap NFL Hoddies Cheap Baseball Hoddies |
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